Jim Wright Selected Research

GTI2501

2/2006

GTI-2501, an antisense agent targeting R1, the large subunit of human ribonucleotide reductase, shows potent anti-tumor activity against a variety of tumors.

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Jim Wright Research Topics

Disease

9	Neoplasms (Cancer) 08/2017 - 06/2003
3	Neoplasm Metastasis (Metastasis) 04/2007 - 06/2003
2	Lung Neoplasms (Lung Cancer) 09/2021 - 08/2017
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 09/2021 - 08/2017
2	Prostatic Neoplasms (Prostate Cancer) 01/2020 - 04/2012
2	Renal Cell Carcinoma (Grawitz Tumor) 01/2009 - 06/2003
2	Melanoma (Melanoma, Malignant) 02/2006 - 06/2003
2	Astrocytoma (Pilocytic Astrocytoma) 02/2006 - 06/2003
2	Lymphoma (Lymphomas) 02/2006 - 06/2003
2	Glioblastoma (Glioblastoma Multiforme) 02/2006 - 06/2003
1	Squamous Cell Carcinoma of Head and Neck 02/2020
1	Malaria 11/2017
1	Fever (Fevers) 11/2017
1	Colonic Neoplasms (Colon Cancer) 09/2009
1	Breast Neoplasms (Breast Cancer) 06/2003
1	Burkitt Lymphoma (Burkitt's Lymphoma) 06/2003
1	Adenocarcinoma 06/2003

Drug/Important Bio-Agent (IBA)

4	Ribonucleotide Reductases (Ribonucleotide Reductase)IBA 01/2009 - 06/2003
2	Metformin (Glucophage)FDA LinkGeneric 09/2021 - 08/2017
2	Antineoplastic Agents (Antineoplastics)IBA 09/2009 - 06/2003
2	Transcription Factors (Transcription Factor)IBA 09/2009 - 02/2006
2	Antisense OligonucleotidesIBA 01/2009 - 02/2006
2	GTI2040IBA 01/2009 - 06/2003
2	Proteins (Proteins, Gene)FDA Link 11/2006 - 02/2006
1	AndrogensIBA 01/2020
1	AMP-Activated Protein KinasesIBA 08/2017
1	Docetaxel (Taxotere)FDA Link 04/2012
1	Neoplasm Antigens (Tumor Antigens)IBA 04/2012
1	SolventsIBA 04/2012
1	AntigensIBA 04/2012
1	ZincIBA 09/2009
1	2- (2- methyl- 1H- indol- 3- yl)- 1H- imidazol(4,5- f)(1,10)phenanthrolineIBA 09/2009
1	Interferon-alpha (Interferon Alfa)IBA 01/2009
1	Small Interfering RNA (siRNA)IBA 04/2007
1	tanespimycin (17AAG)IBA 11/2006
1	Biological ProductsIBA 11/2006
1	Bortezomib (Velcade)FDA Link 11/2006
1	Proteasome InhibitorsIBA 11/2006
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 11/2006
1	GTI2501IBA 02/2006
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 02/2006
1	Pharmaceutical PreparationsIBA 02/2006
1	ThioredoxinsIBA 02/2006
1	Messenger RNA (mRNA)IBA 02/2006
1	OligonucleotidesIBA 06/2003

Therapy/Procedure

2	Radiotherapy 02/2020 - 01/2020
2	Therapeutics 01/2020 - 08/2017
1	Chemoradiotherapy 09/2021
1	Oral Surgery (Maxillofacial Surgery) 02/2020
1	Insecticide-Treated Bednets 11/2017